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Vaccine Weekly

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Cancer Vaccine



Dendritic/tumor-fusion vaccine provides good clinical responses



May 10th, 2006

Cancer immunotherapy using a dendritic/tumor-fusion vaccine induces elevation of serum anti-nuclear antibody with good clinical responses.

"Dendritic cell (DC) vaccines might induce both anti-tumor immunity and autoimmunity. In this report, we demonstrate elevated levels of anti-nuclear antibody (ANA) in the sera of patients with cancer who had received immunotherapy with a dendritic/tumor-fusion vaccine," stated investigators in Japan.

"Twenty-two patients were treated with DC vaccine of fusion cells composed of autologous DCs and tumor cells (DC/tumor-fusion vaccine), which was generated by treating each cell type with polyethylene glycol," said...


Source: Vaccine Weekly (2006-05-10)

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