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Vaccine Weekly

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DNA



Recent findings in DNA described by researchers from Japan, Belgium and Ireland



May 10th, 2006

DNA research advances have been reported from Japan, Belgium and Ireland.

Study 1: According to a study from Japan, a DNA vaccine using hemagglutinating virus of Japan-liposome encapsulating combination encoding mycobacterial heat shock protein 65 (Hsp65) and interleukin-12 (IL-12) confers protection against Mycobacterium tuberculosis by T cell activation.

"We investigated the immunogenicity and protective efficacy of DNA vaccine combinations expressing mycobacterial Hsp65 and IL-12 using gene gun bombardment and the hemagglutinating virus of Japan (HVJ)-liposome method," wrote S. Yoshida and colleagues of the National Hospital in...


Source: Vaccine Weekly (2006-05-10)

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