Herpes Simplex Virus
Herpes virus virions can enter cells via cognate receptor
Published in Vaccine Weekly, May 10th, 2006
According to researchers in the United States, "Earlier this laboratory constructed a herpes simplex virus 1 recombinant (R5111) that carries a IL13 ligand inserted into glycoprotein D and can enter cells via the IL13R alpha 2 receptor commonly expressed on the surface of malignant glioma cells. In this report, we describe the properties of two recombinant viruses carrying chimeric gD genes."
"In R5181 recombinant virus the chimeric gene consisted on the residues 20-155 of urokinase...
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Source: Vaccine Weekly (2006-05-10)
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