Published in Vaccine Weekly, May 17th, 2006
Study 1: A PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation induces CTL capable of lysing human tumors.
According to recent research from the United States, "Fusion proteins created by chromosomal translocations in tumors can create neo-antigenic determinants at the breakpoint, which are unique to the tumor cells but shared by the vast majority of tumors of that histologic type. If the fusion protein is responsible for the malignant transformation, its...
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Source: Vaccine Weekly (2006-05-17)
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