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Apoptosis

Findings from Australia, Germany and Italy describe new data in apoptosis research

Published in Vaccine Weekly, May 24th, 2006

Apoptosis research advances have been reported from Australia, Germany and Italy.

Study 1: Varicella-zoster virus ORF63 inhibits apoptosis of primary human neurons.

"Virus-encoded modulation of apoptosis may serve as a mechanism to enhance cell survival and virus persistence. The impact of productive varicella-zoster virus (VZV) infection on apoptosis appears to be cell type-specific, as infected human sensory neurons are resistant to apoptosis, yet human fibroblasts readily become apoptotic. We sought to identify the viral gene product responsible for this anti-apoptotic phenotype in primary human sensory neurons," scientists in Australia and the...

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