Published in Vaccine Weekly, May 24th, 2006
Study 1: Scientists have developed a method to target DNA vaccines to the skin.
According to recent research from the United States, "The Achilles heel of gene-based therapy is gene delivery into the target cells efficiently with minimal toxic effects. Viral vectors for gene/DNA vaccine delivery are limited by the safety and immunological problems. Recently, nonviral gene delivery mediated by electroporation has been shown to be efficient in different tissues including skin. There are no detailed reports about the effects of electroporation on skin tissue, when...
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