Vaccine Weekly

Chancroid Vaccine -  Haemophilus ducreyi hemoglobin receptor protects against chancroid

Drug Development - Directed antigen delivery is vaccine strategy for intracellular bacterial pathogens

Environmental Health - Soot immunization elicits antibodies against polycyclic aromatic hydrocarbons

Epidemiology - Pneumococcal conjugate vaccine reduces invasive pneumococcal disease among infants

Pneumococcal Vaccine - DNA vaccines expressing pneumococcal surface protein A are as protective as recombinant protein

Alzheimer Disease - Anti-A-beta antibodies do not prevent neurofibrillary tangle formation

Alzheimer Disease - Metabolism of amyloid beta peptide and pathogenesis of Alzheimer disease are focus of review

Anthrax Vaccine - U.S. HHS buys 5 million additional doses of AVA anthrax vaccine from BioPort

Apoptosis - Multiple roles for calcium signaling in apoptosis of cancer cells exposed to diindolylmethane revealed

Avian Influenza Vaccine - sanofi pasteur H5N1 pandemic influenza vaccine candidate demonstrates significant immune response

Avian Influenza Vaccine - St. Jude test of avian influenza vaccine protects mice and ferrets, researchers report

Awards - Dr. Walter Orenstein delivers Stanley A. Plotkin Lecture in Vaccinology

Awards - Dynavax scientist receives 'European Inventor of the Year' award

Bladder Cancer - Bladder cancer prophylaxis achieved with intravesical bacille Calmette-Guerin

Breast Cancer - Breast cancer apoptosis inhibited by progestin

Breast Cancer - Breast cancer inhibited by melatonin

Breast Cancer - Breast cancer treatment by LJ-529 proposed

Breast Cancer Vaccine - Celecoxib enhances efficacy of dendritic cell vaccines against breast cancer

Business Update - Crucell presents update on strategy and operations at analyst briefing

Business Update - FFF Enterprises announces successful launch of U.S. flu vaccine distribution innovation

Cancer Gene Therapy - Multiple oncolytic herpes simplex virus vectors generated

Cancer Research - OMA and Aveo to use human engineering technology to humanize AV-299

Cancer Therapy - BMS-275183 showed promising antitumor activity

Cancer Vaccine - Cancer testis antigen importance in cancer immunotherapy of cancer is focus of review

Cancer Vaccine - Heat shock protein 105-pulsed dendritic cells cause tumor rejection

Cancer Vaccine - Selective cytotoxic T-lymphocytes target tumor immune escape variants

Cervical Cancer Vaccine - HPV vaccines show promise for low-grade intraepithelial disease

Chickenpox Vaccine - Ethnic disparities have been eliminated for varicella vaccination in U.S. children

Cholera Vaccine - Noncovalent quaternary structure of cholera toxin has been characterized

Collaborations - Baxter to participate in development of vaccines for U.S. Department of Health and Human Services

Collaborations - Circadian Technologies Limited announces major agreement with Ludwig Institute and Licentia

Collaborations - Cobra Biomanufacturing to work with International AIDS Vaccine Initiative and GSK Biologicals

DNA Vaccine - Transfection of cells was effective with multishell calcium phosphate-DNA nanoparticles

DPT Immunizations - Pertussis booster plus diphtheria and tetanus toxoids is safe and effective in adolescents

Drug Development - Adeno-associated viral vectors can aid treatment of neurological disorders

Drug Development - AZ703 proposed as novel selective imidazo[1,2-a]pyridine cyclin-dependent kinase inhibitor

Drug Development - Coley Pharmaceutical Group announces data from clinical study of ACTILON for hepatitis C

Drug Development - Gelatin nanoparticles are taken up by dendritic cells

Drug Development - Herpesvirus has been designed to enter cells solely via IL-13 alpha 2 receptor

Drug Development - Idiotypic TCR beta-chain immunization generates antigen-specific T cell response

Drug Development - Influenza protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors

Drug Development - Modified montmorillonite functions as vector for gene delivery

Drug Development - Protein-loaded microparticles for antigen delivery to dendritic cells have been prepared

Enteric Fever -  Salmonella enterica Paratyphi A and Typhi cause indistinguishable syndromes

Epidemiology - Program reduces vaccine-preventable diseases in Bedouin population

Epidemiology - Severe pediatric influenza has implications for immunization recommendations

Epidemiology - Variation in measles-mumps-rubella immunization coverage is examined

Finance - Iomai submits proposal to U.S. HHS for funds to develop pandemic influenza skin patch

Finance - Targeted Genetics reports Q1 2006 $3.7 million net loss compared to $4.7 million a year ago

Gastric Cancer Vaccine - Secernin 1 is identified as immunotherapy target for gastric cancer

Geriatrics - Pneumococcal vaccine plus CpG ODN restores defective IgG responses in aged mice

HIV/AIDS Pathogenesis - Intestinal double-positive CD4+CD8+ T cells have increased cytokine production capacity

HIV/AIDS Research - Tanox reports positive results at 48 weeks in phase 2 dosing trial of HIV drug candidate

HIV/AIDS Therapy - Enrollment for phase 2 stage 1 monotherapy study of oral entry inhibitor completed

HIV/AIDS Vaccine - Anti-dendritic cell HIV gag fusion antibody vaccine intensified CD4+ T cell immunity

Immunotherapy - Chemokines enhance immunity by guiding T cells to CD4 T cell-dendritic cell interaction sites

Immunotherapy - Immunomodulative chemotherapy enhances Th2 responses to herpesvirus vectors

Immunotherapy - Nitric oxide is involved in effects of streptococcal antitumor agent

Influenza Vaccine - Federal program to promote influenza vaccination in elderly is cost-effective

Influenza Vaccine - Intranasal lipopeptide primes lung memory CD8+ T cells for influenza protection

Influenza Vaccine - Prospects for universal influenza virus vaccine are focus of review

Malaria Vaccine -  Plasmodium berghei infection boosts antibody responses primed by DNA vaccine

Malaria Vaccine -  Plasmodium berghei vaccine protects against liver-stage malaria

Malaria Vaccine - Nematode infection reduces protective efficacy of blood-stage malaria vaccine

Measles Vaccine - No measles virus genome sequence was detected in blood of autistic children

Medical Statistics - Instrumental variable method is useful to study self-selection mechanism

Meningitis Therapy - Pneumococcal meningitis management and prevention approaches are focus of review

Ovarian Cancer - Ovarian cancer could be treated by Survivin and Granzyme B-induced apoptosis

Ovarian Cancer - Ovarian cancer inhibited by M344, a novel histone deacetylase inhibitor

Patents - Aphios awarded U.S. patent for HIV/AIDS, influenza vaccines

Pediatrics - Features of infants at risk for Haemophilus influenzae type b disease are described

Personnel - Dr. Robert V. House appointed president of CSC's DVC LLC vaccine business

Personnel - Novavax board elects Dr. James B. Tananbaum as director

Poliovirus Vaccine - Neutralizing antibodies against poliovirus serotypes in Nigeria have been identified

Prion Disease - RNA interference suppresses prion protein in livestock