Immunotherapy
Chemokines enhance immunity by guiding T cells to CD4 T cell-dendritic cell interaction sites
Published in Vaccine Weekly, May 31st, 2006
According to recent research from the United States, "CD8+ T cells have a crucial role in resistance to pathogens and can kill malignant cells; however, some critical functions of these lymphocytes depend on helper activity provided by a distinct population of CD4+ T cells. Cooperation between these lymphocyte subsets involves recognition of antigens co-presented by the same dendritic cell, but the frequencies of such antigen-bearing cells early in an infection and of the relevant naive T cells are both low. This suggests that an active mechanism facilitates the...
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Source: Vaccine Weekly (2006-05-31)
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