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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . June 14th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Addiction Medicine - Bivalent morphine/heroin vaccine prevents relapse to heroin addiction

Dengue Vaccine - Fusion protein dengue vaccine is protective in nonhuman primates

Human Papillomavirus Vaccine - Parental acceptance of adolescent HPV vaccine is critical for success

Influenza Vaccine - Influenza A NP-expressing vaccinia virus protects against human and avian influenza

Influenza Vaccine - Influenza vaccine containing A/Panama/1999 induces broad protection against influenza

Adenovirus Vaccine - Adenoviral respiratory illness in U.S. military recruits is increasing

Alzheimer Disease Vaccine - Effects of immunization with A-beta1-42 in canines were characterized

Apoptosis - Melanoma apoptosis triggered by novel Bcl-x splice product, Bcl-x(AK)

Business & Finance - Chembio reports 238% increase in net product sales over same period last year

Business & Finance - DOR BioPharma, Inc. reports first quarter financials, reviews achievements

Cancer Therapy - Squamocin inhibits proliferation of leukemia cells via G2/M arrest

Cancer Therapy - Tumor cells selectively affected by natural flavonoids and synthetic derivatives

Cancer Vaccine - Advaxis continues advancement of listeria vaccines targeting cancers affecting women

Cancer Vaccine - Antigen delivery to antigen-presenting cells using penetratin induces potent immune responses

Cancer Vaccine - DNA-based cancer vaccine enhances lymphocyte cross-talk by engaging NKG2D receptor

Cancer Vaccine - Double loading of dendritic cells with AML antigen enhances T cell immunity

Cancer Vaccine - Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates has been developed for cancer vaccine

Cancer Vaccine - ITAC vaccination attenuates disseminated metastases of circulating tumor cells

Cancer Vaccine - MUC1/IL-18 DNA vaccine induces antitumor immunity and increased survival

Cancer Vaccine - New assays for immune monitoring in cancer vaccine development are needed

Cancer Vaccine - Regulatory considerations for nonclinical cancer vaccine development are discussed

Chickenpox Vaccine - Chickenpox can complicate pregnancy

Chlamydia Vaccine - Mouse model of respiratory Chlamydia pneumoniae infection has been developed

Clinical Trials - Hemispherx announces influenza vaccine/immunopotentiation clinical trials

Colorectal Cancer Vaccine - CD137 and CD137 ligand expression in colorectal cancer are focus of review

Coxsackievirus Vaccine - Liposome-mediated transfection reduces coxsackievirus infectivity

DNA Vaccine - Analysis of codon adaptation index of Boophilus microplus bm86 gene optimizes DNA vaccine

DNA Vaccine - DNA is better than protein vaccine for Choristoneura ecdysone receptor antibody production

DNA Vaccine - Porcine reproductive and respiratory syndrome virus vaccine displays enhanced immunogenicity

Dental Research - Collagen-binding by strep protein associated with dental caries and endocarditis

Drug Development - Combretastatin nitrogen-containing derivatives developed as vascular disrupting agents

Drug Development - Dendreon presents data on potential new active immunotherapy for treating renal cell cancer

Drug Development - HIV-derived lentiviral vectors transduce murine cerebellar Purkinje cells

Drug Development - Idera broadens toll-like receptor programs, presents new data

Encephalomyelitis Vaccine - Intrasplenic electro-transfer of IL-4 encoding plasmid DNA inhibits encephalomyelitis

Enterovirus Vaccine - Transgenic tomato fruit expressing VP1 protein from enterovirus 71 was used to immunize mice

Finance - Iomai reports net loss in Q1 2006 of $5.5 million compared to $5 million in Q1 2005

Finance - MacroGenics raises $45 million in series C financing

Foot-and-Mouth Disease Vaccine - Emergency foot-and-mouth disease vaccine increases protection in cattle

Gene Research - Canine X-linked severe combined immunodeficiency was corrected by gene therapy

HIV/AIDS Vaccine - Fusion to TNF alpha cDNA enhances immune responses to HIV gp 120 DNA vaccine

HIV/AIDS Vaccine - PCR assay determines replication capacity for HIV-1 protease and reverse transcriptase variants

HIV/AIDS Vaccine - Subtype C in-frame gagpol fusion gene vaccine shows promise against HIV/AIDS

Haemophilus Vaccine -  Haemophilus influenzae type b vaccination is recommended for patients with beta-thalassemia

Hantavirus Vaccine - Vesicular stomatitis virus containing Hantaan virus envelope glycoproteins was used for vaccine

Healthcare Policy - Catholic Medical Association calls for vaccines not associated with abortion

Helicobacter Pylori - Critical regulators of beta-defensins during H. pylori infection are identified

Hepatitis B Outbreak - Methamphetamine injectors are at high risk for hepatitis B virus infection

Hepatitis B Virus - HBV protective antibody is prevalent following HAART in HIV-infected children

Hepatitis B Virus - Hepatitis B surface antigen and antibody persistence causes lesions

Hepatitis C Therapy - Coley's ACTILON for chronic hepatitis C virus therapy granted Fast Track designation

Hepatitis C Virus - HCV DNA vaccine potency is enhanced by Mycobacterium HSP70 gene fragment

Herpes Simplex Virus Epidemiology - HSV-1 and HSV-2 seroprevalence determined in Australia

Human Papillomavirus Vaccine - Efficiency of HPV 16 L1/E7 DNA immunization is reported

Human Papillomavirus Vaccine - Improved HPV DNA vaccine candidate induces a wild-type-specific T cell response

Imaging - DNA vaccine gene expression imaged using firefly luciferase as a naked DNA

Influenza - High-dose flu vaccines appear to boost immunity in elderly without significant side effects

Influenza Vaccine - High-risk adults benefit from first influenza vaccination

Influenza Vaccine - Influenza vaccine safe is in patients with stable lupus or rheumatoid arthritis

Influenza Vaccine - Mitigation strategies for pandemic influenza in U.S. are presented

Legal Issues - Dauphin Technology Inc. and preferred shareholders settle and dismiss legal actions

Leishmaniasis Vaccine - KM+ lectins enhance vaccine efficacy against Leishmania amazonensis

Leishmaniasis Vaccine - Stimulatory soluble proteins have prophylactic potential against visceral leishmaniasis

Leishmaniasis Vaccine - Three vaccination strategies against Leishmania major were compared

Leukemia Vaccine - Enhanced sensitivity to SHP2, STAT5, and Gab2 inhibition were found in chronic myeloid leukemia

Lung Cancer - Lung cancer cell death induced by chloroquine diphosphate

Lung Cancer Vaccine - Cancer-testis antigens show promise for non-small cell lung cancer therapeutics

Lung Cancer Vaccine - Foxp3 expression is higher in lung cancer than in normal tissues

Malaria Vaccine - Clinical trial of candidate malaria vaccines RTS,S/AS02A and MVA-CS is reported

Marburg Virus Vaccine - Marburg virus antigens from adenovirus vectors induce potent immune responses

Measles Vaccine - Serology indicates greater measles vaccine coverage than immunization records

Melanoma Vaccine - Allogeneic and autologous melanoma vaccines are the focus of review

Melanoma Vaccine - Cytokine-based therapy for advanced melanoma is the focus of review

Melanoma Vaccine - Immunosuppression in melanoma immunotherapy offers intervention opportunities

Melanoma Vaccine - Melanoma vaccines must boost immune response and prevent tumor cell evasion

Melanoma Vaccine - Overcoming immune resistance mechanisms in melanoma microenvironment is discussed

Meningococcal Vaccine - IgG subgroup response to meningococcal vaccine is described

Monoclonal Antibodies - Antibody specific to VP19 envelope protein of white spot syndrome virus has been developed

Mycobacterial Vaccine - Anti-CD3 single-chain Fv/IL-18 fusion DNA induces antimycobacterial resistance

Nicotine Vaccine - Nicotine-specific antibodies differently affect acute and chronic distribution of nicotine to brain

Obstetrics - Rubella infection in pregnancy is focus of review

Ovarian Cancer - Ovarian cancer apoptosis induced by epigallocatechin-3-gallate

Patents - Carrington gets added U.S. patent protection for antigen-sparing influenza vaccines

Personnel - Donald Beeman named chief executive officer of LigoCyte Pharmaceuticals

Personnel - Intercell, AG appoints two senior executives to the supervisory board

Pertussis Vaccine - Immune responses to acellular pertussis vaccines were skewed toward Th1 type

Plague Vaccine - Microsphere delivery of Yersinia pestis antigen induces immune responses

Pneumococcal Conjugate Vaccine - Adding fourth heptavalent pneumococcal vaccine to MMR, varicella, and Hib vaccines is safe

Pneumococcal Vaccine - Method for evaluating antipneumococcal surface adhesin A antibodies has been developed

Pneumococcal Vaccine - Number of doses of pneumococcal conjugate vaccine may be reduced in children

Pneumococcal Vaccine - Pneumococcal vaccine is changing bacteremia epidemiology in children

Preventive Medicine - Study provides road map to preventive services with greatest health impact, best cost value

Product Licensing - Inovio acquires rights to augment patent estate for electroporation-assisted nucleic acid delivery

Protein Production - Plasmid expression vectors for production of proteins in Bacillus subtilis have been developed

Protein Production - Tagged E. coli proteins were overexpressed using chromosomal knock-in strategy

Proteomics - Method for rapid molecular dissection of viral and bacterial immunomes has been developed

Rotavirus Vaccine - Immunity and correlates of protection for rotavirus vaccines are the focus of review

Rotavirus Vaccine - Maternal antibodies suppress B cells induced by rotavirus vaccine

SARS Vaccine - Nucleocapsid protein-based SARS vaccine candidates are characterized

Streptococcal Vaccine - Opsonophagocytic assays to identify Streptococcus pneumoniae antibodies were evaluated

Tetanus Vaccine - Immune response model to determine tetanus vaccine-specific immunogenicity has been developed

Tuberculosis Vaccine - BCG vaccine is effective in children with extrapulmonary but not pulmonary TB

Vaccine Adjuvant - Chemokine CXCL10 is sufficient to trigger immune response to injected antigens

Vaccine Development - Anti-TNF antibodies are the focus of review

Vaccine Development - Study reveals a new way of looking at vaccine development

Vaccine Efficacy - Choice of vaccine adjuvant affects T cell polarization

Vaccine Efficacy - HIV challenge assay has been developed using luciferase-expressing vaccinia virus

Vaccine Efficacy - Long-lived CD8+ T cells are programmed by prolonged antigen exposure

Vaccine Vector - Adenovirus-expressing capsid protein of porcine circovirus 2 has been constructed

Yellow Fever Vaccine - Yellow fever booster response is affected by prevaccination serology

Breast Cancer - Data from Italy and the United States advance knowledge in breast cancer research

Breast Cancer - Reports from the People's Republic of China, United States and Sweden add new data to breast cancer research

Cancer Treatment - Findings from the United States advance knowledge in cancer treatment research

Cancer Treatment - New data from Japan and the United States lluminates research in cancer treatment

Cancer Treatment - Recent findings in cancer treatment described by researchers from Japan, the People's Republic of China and Sweden

Cancer Treatment - Reports from the United States and Japan add new data to cancer treatment research

Cancer Treatment - Research from the People's Republic of China, Spain and Denmark in cancer treatment provides new insights

Cancer Treatment - Researchers from Belgium, China and Japan provide details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from Germany, Japan and the United States describe findings in cancer treatment studies

Cancer Treatment - Researchers from Japan, Switzerland and Germany report recent findings in cancer treatment

Cancer Treatment - Researchers' data from the United States and Brazil advance cancer treatment research

Cancer Treatment - Researchers' findings from the United States advance cancer treatment research

Chickenpox - Studies from the United States, Australia and Taiwan advance knowledge in chickenpox research

DNA - Recent studies from the People's Republic of China, United States and Japan add new data to DNA research

DNA - Studies from the United States advance knowledge in DNA research

Diabetes - Researchers from South Korea, Finland and Sweden detail new studies and findings in the area of diabetes

HIV/AIDS - Reports from the United States add new data to HIV/AIDS research

HIV/AIDS - Reports from the United States and Italy advance knowledge in HIV/AIDS research

HIV/AIDS - Researchers from South Africa and Italy provide details of new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers from the United States and United Kingdom describe findings in HIV/AIDS studies

Helicobacter - Researchers from Sweden, Germany and Switzerland report details of new studies and findings in the area of helicobacter

Helicobacter - Researchers from the United Kingdom, Germany and Japan provide details of new studies and findings in the area of helicobacter

Hepatitis B Virus - Findings from the United States advance knowledge in hepatitis B virus research

Hepatitis C Virus - Researchers from Cuba, Italy and Spain provide details of new studies and findings in the area of hepatitis C virus

Influenza - Findings from the United States, Brazil and United Kingdom describe new data in influenza research

Influenza - Research from the United States in influenza provides new insights

Influenza - Researchers from Italy, the United Kingdom and Chile provide details of new studies and findings in the area of influenza

Influenza - Researchers from Japan and the United States detail new studies and findings in the area of influenza

Influenza - Researchers from the United States and United Kingdom report recent findings in influenza

Leishmania - New findings in leishmania described from India, Germany and the United States

Leukemia - Research from Thailand, Germany and Belgium in leukemia provides new insights

Listeria - Researchers from Canada, Germany and the United States describe findings in listeria studies

Lung Cancer - Data from France, Italy and the United States advance knowledge in lung cancer research

Lung Cancer - New research from Spain, France and Greece in the area of lung cancer detailed

Lung Cancer - Reports from Mexico, Japan and Germany add new data to lung cancer research

Malaria - Researchers from the United States and Australia publish new studies and findings in the area of malaria

Measles - Researchers from Japan and the United States report details of new studies and findings in the area of measles

Meningitis - New findings from Cuba, the United Kingdom and Switzerland in the area of meningitis described

Neurology - Reports from the United States and Canada add new data to neurology research

Papillomavirus - Reports from Germany, Netherlands and the United States advance knowledge in papillomavirus research

Pneumococcal - New findings in pneumococcal described from the United States and Greece

Pneumococcal - New research from Netherlands, Italy and United States in the area of pneumococcal detailed

Pneumococcal - Studies from the United States and Kenya describe new findings in pneumococcal research

Polio - Recent findings in polio described by researchers from the United States and South Africa

Prostate Cancer - New findings from Canada and the United States in the area of prostate cancer detailed

Proteins - Findings from Canada, Sweden and the United States in proteins provide new insights

Respiratory System - Researchers from the People's Republic of China, Argentina and United States detail new studies and findings in the area of respiratory system

Rotavirus - Researchers from the United States and France provide details of new studies and findings in the area of rotavirus

SARS - Studies from the People's Republic of China and Taiwan advance knowledge in SARS research

Schistosomiasis - Studies from Brazil and the People's Republic of China add new findings to schistosomiasis body of knowledge

Streptococcus - New findings from Germany, Brazil and the United States in the area of streptococcus detailed

Stroke - Researchers from the United Kingdom, South Korea and France report recent findings in stroke

Tuberculosis - Findings from Mexico, the United States and India describe new data in tuberculosis research

Tuberculosis - Researchers from the United Kingdom, India and Kuwait detail new studies and findings in the area of tuberculosis

Tuberculosis - Researchers from Wales, Switzerland and Turkey publish new studies and findings in the area of tuberculosis

Vaccines - Data from Australia, Spain and the United States advance knowledge in vaccines research

Vaccines - Findings from the United States, United Kingdom and France in vaccines provide new insights

Vaccines - Recent studies from Canada and the United States add new data to vaccines research

Vaccines - Reports from Japan and the United States add new data to vaccines research

Vaccines - Reports from the United States and Japan advance knowledge in vaccines research

Vaccines - Research from Austria, Iceland and the United States add new data to vaccines body of knowledge

Vaccines - Research from Taiwan, the United States and the United Kingdom add new data to vaccines body of knowledge

Vaccines - Researchers from the United States and Austria report details of new studies and findings in the area of vaccines

Vaccines - Researchers' findings from Sweden, Cuba and the United States advance vaccines research

Vaccines - Studies from Japan, India and Canada describe new findings in vaccines research

Vaccines - Studies from Switzerland, the United States and Australia advance knowledge in vaccines research

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