Vaccines
Research from Austria, Iceland and the United States add new data to vaccines body of knowledge
Published in Vaccine Weekly, June 14th, 2006
Study 1: Immunization of Rhesus monkeys with the conjugate vaccine IGN402 induces an IgG immune response against carbohydrate and protein antigens and cancer cells.
Scientists writing in the journal Vaccine report, "Tumor-associated antigens resulting from aberrant glycosylation, such as the SialylTn carbohydrate antigen, are overexpressed on cancer cells and provide potential targets for cancer vaccination. However, as T-cell-independent antigens carbohydrates are poorly immunogenic, and fail to induce memory. In order to increase the immunogenicity we...
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Source: Vaccine Weekly (2006-06-14)
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