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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . July 5th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Allergy Medicine - DNA vaccines and allergic diseases reviewed

Alzheimer Disease Vaccine - Anti-A-beta single-chain antibody reduces amyloid load in Alzheimer mouse model

Escherichia Coli Vaccine - Plant-based vaccine protects against intoxication by Shiga toxin

SARS Vaccine - Amino acid substitution in SARS coronavirus spike protein disrupts binding

Streptococcal Vaccine - Rhesus macaque model to assess Streptococcus pneumoniae vaccines developed

Adaptive Immune Response - IFN-alpha/beta-dependent cross-priming induced by specific toll-like receptor agonists

Allergy & Immunology - Dynavax announces completion of enrollment in Tolamba ragweed allergy trial

Avian Influenza - Tamiflu supply in Tijuana, Mexico, attracts bird flu-wary Americans, Medicine Store says

Biotechnology - Pathogenic bacterial strategies are exploited for use in biotechnology

Bladder Cancer - Bladder cancer treated by intravesical instillations with bacillus Calmette-Guerin

Breast Cancer - Breast cancer patients tolerated bortezomib but showed limited response

Breast Cancer Vaccine - Transfected fibroblasts enhance immunity to breast cancer

Cancer Gene Therapy - Introgen's advexin p53 therapy data show beneficial clinical activity in inherited cancer

Cancer Therapy - Anticancer and antimetastatic properties of doenjang increased with longer aging time

Cancer Therapy - Epoetin alfa dosing as initiation treatment in chemotherapy-related anemia studied

Cancer Therapy - Targeted molecular therapy, erlotinib HC1 combination inhibits tumor growth, studies show

Cancer Therapy - Tumors targeted by adoptive transfer of immune cells

Cancer Vaccine - Gamma-chain cytokines compared for generation of tumor-reactive T lymphocytes

Cancer Vaccine - Granzyme B ELISPOT assay used for monitoring cancer vaccine trials

Cancer Vaccine - Immune suppression in tumor microenvironment reviewed

Cancer Vaccine - STXA1-GM-CSF protein exhibits selective cytotoxicity in hematopoietic cancer cells

Cancer Vaccine - Ubiquitin-proteasome system plays key role in presenting CTL epitope to CD8+ T cells

Cancer Vaccines - Celldex Therapeutics presents EGFRvIII vaccine data at ASCO meeting

Cell Therapy - Photodynamic therapy plus intratumoral naive DC injection induces antitumor immunity

Central Nervous System - Therapeutic vaccination for central nervous system repair reviewed

Cervical Cancer - Inventors praise U.S. Food and Drug Administration's approval of vaccine for cervical cancer

Cervical Cancer - Study shows HPV DNA testing about 40% more sensitive than conventional, liquid based PAPs

Chemotherapy Side Effects - Etoposide-induced alopecia suppressed by MMK-1 bound to FPRL1 receptor

Chronic Myelogenous Leukemia - Cell Genesys reports long-term follow-up data from Phase 2 trial of GVAX immunotherapy in CML

Conjugated Vaccine Development - Method developed for obtaining conjugated vaccines

DNA Vaccine - Gene therapy method for articular cartilage lesions using naked DNA developed

Drug Delivery - Solid tumors received delivery of docetaxel via lipid nanocapsules

Drug Delivery - Soluble polymers and polymer microparticles improve vaccine response

Drug Development - Cell Genesys and Medarex announce interim results from Phase 1 combination therapy trial

Drug Development - Cytotoxic cyclodepsipeptide isolated from marine fungus Clonostachys sp ESNA-A009

Drug Development - DNA microarray technology for target identification reviewed

Drug Development - Neuroblastoma cell death induced by docosahexaenoic acid warrants further study

Finance - Baxter foundation awards $600,000 in grant monies to improve healthcare access

HIV/AIDS Advocacy - National Minority Health Month Foundation calls on Congress to Pass Ryan White CARE Act

HIV/AIDS Vaccine - AIDS vaccine research offers new insights on survival

HIV/AIDS Vaccine - Dendritic cell vaccine elicits mixed responses in patients with HIV-1 infection

Hepatocellular Cancer Vaccine - Dendritic cells pulsed with alpha-fetoprotein peptides (AFP) elicit AFP-specific T cells

Hepatocellular Cancer Vaccine - HLA-A2- or HLA-A24-restricted CTL epitopes for liver cancer therapy identified

Influenza Vaccine - Scientists show cross-strain protection may be best defense against future influenza outbreaks

Japanese Encephalitis Vaccine - Intercell's Japanese encephalitis virus vaccine met primary endpoint in phase III trial

Leishmaniasis Vaccine - Sodium antimony gluconate induces reactive oxygen species in Leishmania-infected macrophages

Leukemia - Interim darbepoetin alfa data suggest major response in treating anemia in MDS patients

Malaria Immunity - Malaria protection associated with antibodies against merozoite surface protein 1 N terminus

Marburg Hemorrhagic Fever Vaccine - Replication-competent vaccine provides postexposure protection against Marburg virus

Market Analysis - Annual 3.4% growth in prostate cancer drug market spurred by new therapies, study shows

Measles Epidemiology - Confirmed cases of measles by region and age in U.S. reported

Melanoma - Phase 2 data show ipilimumab extended dosing well tolerated in adjuvant melanoma vaccine

Melanoma Vaccine - Liposome-TRP2 peptide and CpG DNA elicit cytotoxic T lymphocytes against melanoma

Multiple Myeloma - Multiple myeloma cell growth predominantly stimulated by bone-derived IGFs

Pain Management - First patient enrolled in phase 3 pain study for injectable NSAID diclofenac sodium

Prostate Cancer - Cell Genesys recaps two presentations from 2006 ASCO Annual Meeting

Prostate Cancer - Ipilimumab 1 and 2 trial data positive in hormone refractory prostate cancer patients

Prostate Cancer - Prostate-specific membrane antigen antibody-drug conjugate has potent antitumor activity

Protein Deficiency Diseases - Inovio shows electroporation's potential to deliver gene-based treatments

SARS Vaccine - Epitopes in SARS coronavirus nucleocapsid and spike proteins described

Smallpox Vaccine - Electronic monitoring system to assess vaccination responses developed

Solid Cancer - Solid cancer dosage linearly related to mean steady-state plasma concentrations of phenoxodiol

Tobacco Use - Smokers invited to test a vaccine against nicotine addiction

Tuberculosis Pathogenesis - Polymeric IgR knockout mice more susceptible to mycobacteria

Tularemia Vaccine -  Francisella tularensis LPS induces cytokine production in monocytes

Vaccine Delivery - Polymeric core-shell nanoparticles for therapeutics developed

Vaccine Design - Adjuvanted vaccines obtained from allergenic mite species developed in Cuba

Vaccinia Virus - Vaccinia-related kinases phosphorylate N' terminus of BAF

Whooping Cough - Whooping cough booster being promoted among moms

Alzheimer Disease - Research from Japan, the United States and Israel in Alzheimer disease provides new insights

Anthrax - Studies from the People's Republic of China and United States describe new findings in anthrax research

Apoptosis - New findings in apoptosis described from Germany and the United States

Breast Cancer - Reports from Italy and the United States describe recent advances in breast cancer research

Cancer Research - Reports from the United States and People's Republic of China describe recent advances in cancer research

Cancer Treatment - Data from the United States and Japan advance knowledge in cancer treatment research

Cancer Treatment - New findings from Germany and the United States in the area of cancer treatment described

Cancer Treatment - Recent findings in cancer treatment described by researchers from the United States and People's Republic of China

DNA - Researchers from the United States, France and Sweden describe findings in DNA studies

Ebola - Findings from the United States describe new data in ebola research

HIV/AIDS - New findings from the United States and United Kingdom in the area of HIV/AIDS detailed

HIV/AIDS - New findings in HIV/AIDS described from the United Kingdom, France and United States

HIV/AIDS - Researchers from the United States report recent findings in HIV/AIDS

Hepatitis B Virus - New research from Germany, India and the United States in the area of hepatitis B virus detailed

Hepatitis C Virus - Research from Cuba and the United Kingdom add new data to hepatitis C virus body of knowledge

Herpes - Researchers from the United States and Japan detail new studies and findings in the area of herpes

Imaging - Research from South Korea and United States in imaging provides new insights

Influenza - Data from Japan, the United States and Israel advance knowledge in influenza research

Influenza - Findings from Germany and the United States describe new data in influenza research

Influenza - Recent studies from the United States and Japan add new data to influenza research

Influenza - Research from Australia, the United Kingdom and the United States add new data to influenza body of knowledge

Influenza - Researchers from Netherlands, United States and United Kingdom provide details of new studies and findings in the area of influenza

Influenza - Researchers' findings from the United States and United Kingdom advance influenza research

Influenza - Studies from Canada, the United States and Norway advance knowledge in influenza research

Leishmania - Researchers from India and the United States describe findings in leishmania studies

Leukemia - New findings from the United States, Belgium and Germany in the area of leukemia detailed

Leukemia - Research from Germany, Italy and the United States add new data to leukemia body of knowledge

Malaria - Findings from Colombia and India advance knowledge in malaria research

Malaria - New data from the United States and Netherlands lluminates research in malaria

Measles - Research from Australia, Mexico and the United States add new data to measles body of knowledge

Measles - Researchers' work from Luxembourg, Netherlands and Russia adds to measles body of knowledge

Measles - Studies from the United Kingdom and United States add new findings to measles body of knowledge

Melanoma - New data from the United States and Germany lluminates research in melanoma

Melanoma - Reports from the United States describe recent advances in melanoma research

Melanoma - Studies from the United States and United Kingdom describe new findings in melanoma research

Meningitis - Reports from Cuba, the United Kingdom and Switzerland advance knowledge in meningitis research

Meningitis - Reports from France, Italy and the United Kingdom add new data to meningitis research

Plague - Studies from India and the United States add new findings to plague body of knowledge

Pneumococcal - Researchers' work from the United States adds to pneumococcal body of knowledge

Polio - Recent findings in polio described by researchers from Nigeria, Japan and Brazil

Proteins - Studies from South Korea and United States add new findings to proteins body of knowledge

Rotavirus - Research from France and the United States add new data to rotavirus body of knowledge

Rotavirus - Studies from Colombia, the United States and Mexico add new findings to rotavirus body of knowledge

SARS - Researchers' data from Taiwan, the United States and the People's Republic of China advance SARS research

Streptococcus - Research from Israel, Japan and the United States add new data to streptococcus body of knowledge

Toxoplasmosis - New findings from France and the United States in the area of toxoplasmosis detailed

Tuberculosis - New findings from Canada, Japan and Kuwait in the area of tuberculosis detailed

Tuberculosis - Research from New Zealand, Switzerland and United States in tuberculosis provides new insights

Tuberculosis - Researchers from Japan, the United Kingdom and the United States report details of new studies and findings in the area of tuberculosis

Tuberculosis - Researchers from the United States, South Africa and United Kingdom publish new studies and findings in the area of tuberculosis

Tularemia - New data from the United States and Sweden lluminates research in tularemia

Vaccines - Data from Japan, Spain and the United States advance knowledge in vaccines research

Vaccines - Data from the United States and Sweden advance knowledge in vaccines research

Vaccines - Findings from Scotland, the Sapporo 060-8638 Japan and the the Netherlands advance knowledge in vaccines research

Vaccines - New findings from the United States in the area of vaccines detailed

Vaccines - Recent studies from the People's Republic of China and Argentina add new data to vaccines research

Vaccines - Reports from the United States advance knowledge in vaccines research

Vaccines - Reports from the United States and Japan advance knowledge in vaccines research

Vaccines - Research from the United States and Kenya add new data to vaccines body of knowledge

Vaccines - Researchers from Germany, Switzerland and Australia provide details of new studies and findings in the area of vaccines

Vaccines - Researchers' data from Australia, Argentina and Mexico advance vaccines research

Vaccines - Studies from Russia, Spain and the United States add new findings to vaccines body of knowledge

Vectors - New findings in vectors described from the United States and Israel

Virology - New research from the United States and Germany in the area of virology detailed

Virology - Researchers from the United States and Turkey detail new studies and findings in the area of virology

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