Published in Vaccine Weekly, July 5th, 2006
Study 1: Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.
"Francisella tularensis is an intracellular Gram-negative bacterium that is the causative agent of tularemia and a potential bioweapon. We have characterized the efficacy of a defined F. novicida mutant (Delta iglC) as a live attenuated vaccine against subsequent intranasal challenge with the wild-type organism," scientists writing in the journal Infection and Immunity...
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