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Tularemia

New data from the United States and Sweden lluminates research in tularemia

Published in Vaccine Weekly, July 5th, 2006

Data on tularemia are outlined in reports from the United States and Sweden.

Study 1: Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.

"Francisella tularensis is an intracellular Gram-negative bacterium that is the causative agent of tularemia and a potential bioweapon. We have characterized the efficacy of a defined F. novicida mutant (Delta iglC) as a live attenuated vaccine against subsequent intranasal challenge with the wild-type organism," scientists writing in the journal Infection and Immunity...

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