Hepatitis B Virus
New research from Germany, India and the United States in the area of hepatitis B virus detailed
Published in Vaccine Weekly, July 5th, 2006
Study 1: The translocation motif of hepatitis B virus improves protein vaccination.
According to recent research from Germany, "Cell-penetrating peptides (CPPs) have been shown to improve antigen loading of dendritic cell vaccines. Here we asked whether fusion of a CPP to a protein improves its immunogenicity when this fusion protein is directly applied as vaccine. We used the cell-penetrating translocation motif (TLM) derived from the hepatitis B virus, because no size limitation of cargos has been observed."
"Increased immunogenicity...
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Source: Vaccine Weekly (2006-07-05)
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