Published in Vaccine Weekly, July 5th, 2006
Study 1: According to a study from Cuba, hepatitis C virus (HCV) core protein enhances the immunogenicity of a co-delivered DNA vaccine encoding HCV structural antigens in mice.
"In the present study, recombinant HCV core proteins enhanced the immune response elicited by a co-delivered DNA vaccine encoding HCV core and envelope proteins. A mixture of the plasmid pIDKE2 and Co. 173, a protein comprising the first 173 amino acids of HCV core, in particular induces a strong humoral response, including antibodies that recognized peptides representing hypervariable...
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Source: Vaccine Weekly (2006-07-05)
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