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Human Papillomavirus

Papilloma lesion regression stimulated by recombinant vaccine

Published in Vaccine Weekly, July 12th, 2006

According to recent research from Mexico, regression of papilloma high-grade lesions (CIN 2 and CIN 3) is stimulated by therapeutic vaccination with MVA E2 recombinant vaccine.

"Human papillomavirus (HPV) is the etiologic agent for cervical cancer. In Mexico, a woman dies every 2 h, and since 1990 the statistics have shown that the numbers of deaths are increasing," wrote E. Garcia-Hernandez and colleagues, Hospital de Gineco Obstetricia.

They continued, "We conducted a phase II clinical trial to evaluate the potential use of the MVA E2 recombinant vaccinia virus in treating high-grade lesions (CIN 2 and CIN 3) associated with oncogenic...

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