Polyoma Virus Vaccine
CD94/NKG2A expression associated with antigen-specific recall of polyoma virus-specific CD8 cells
Published in Vaccine Weekly, July 19th, 2006
According to a study from the United States, "Memory CD8 T cells comprise a critical component of durable immunity because of their capacity to rapidly proliferate and exert effector activity upon Ag rechallenge.
"During persistent viral infection, memory CD8 T cells repetitively encounter viral Ag and must maintain a delicate balance between limiting viral replication and minimizing immunopathology."
"In mice infected by polyoma virus, a natural mouse pathogen that establishes long-term persistent infection, the majority of...
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Source: Vaccine Weekly (2006-07-19)
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