Autoimmune Disease
T cell receptor vaccination in aluminum adjuvant prevents autoimmune encephalomyelitis
Published in Vaccine Weekly, July 26th, 2006
According to a study from Brazil, "Experimental allergic encephatomyetitis (EAE) is a neuro-inflammatory, autoimmune disorder in which myetin-reactive Th1 T cells with a restricted TCRV beta repertoire play a pathogenic role. Here, I show that an engineered single-chain T-cell receptor (TCR) containing dominant TCRV alpha/V beta encephalitogenic elements, when administered in aluminum adjuvant, generates a marked anti-TCR humoral response that correlated with protection against the development of EAE in V beta 8-expressing B10.PL but not in V beta 8-deficient SJL...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
Source: Vaccine Weekly (2006-07-26)
More Articles from Vaccine Weekly
- Human Papillomavirus Vaccine
Papillomavirus high-grade lesion regression stimulated by MVA E2 recombinant vaccine - Influenza Vaccine
T cell responses are better correlates of flu vaccine protection in the elderly - Meningitis Vaccine
Haemophilus influenzae type b reemerges after DTaP-Hib immunization - Pertussis Vaccine
Alleged vaccine encephalopathy may be caused by gene mutations - Vaccine Development
Tobacco mosaic virus particles were used for display of vaccine antigens - Adenovirus Vaccine
Co-infections of adenovirus species were found in previously vaccinated patients - More from this issue of Vaccine Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
