Alzheimer Disease
Research from the United States and Canada in Alzheimer disease provides new insights
Published in Vaccine Weekly, July 26th, 2006
Study 1: Amyloid load was reduced using an anti-A-beta single-chain antibody in an Alzheimer mouse model.
According to recent research from the United States, "Parenteral immunization of transgenic mouse models of Alzheimer disease (AD) with synthetic amyloid beta-peptide (A-beta) prevented or reduced A-beta deposits and attenuated their memory and learning deficits. A clinical trial of immunization with synthetic A-beta, however, was halted due to brain inflammation, presumably induced by a toxic A-beta, T-cell- and/or Fc-mediated immune response. Another issue...
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Source: Vaccine Weekly (2006-07-26)
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