Apoptosis
Researchers from Germany, the People's Republic of China and the United States report details of new studies and findings in the area of apoptosis
Published in Vaccine Weekly, July 26th, 2006
Study 1: Apoptosis in melanoma was triggered by a novel Bcl-x splice product, Bcl-x(AK), implying the existence of new additional mechanisms for apoptosis regulation.
"Pro- and antiapoptotic proteins of the large Bcl-2 family are critical regulators of apoptosis via the mitochondrial pathway. Whereas antiapoptotic proteins of the family share all four Bcl-2 homology domains (BH1-BH4), proapoptotic members may lack some of these domains, but all so far described proapoptotic Bcl-2 proteins enclose BH3," researchers in Germany...
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Source: Vaccine Weekly (2006-07-26)
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