Published in Vaccine Weekly, July 26th, 2006
Study 1: Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs.
According to a scientists in the United States, "Safe induction of autoantigen-specific long-term tolerance is the 'holy grail' for the treatment of autoimmune diseases. In animal models of type 1 diabetes, oral or i.n. immunization with islet antigens induces Tregs that are capable of bystander suppression. However, such interventions are only effective early in the prediabetic phase. We demonstrate that a novel combination treatment with...
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Source: Vaccine Weekly (2006-07-26)
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