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HIV/AIDS Research

Immune Response reports new manufacturing process increases HIV-1 viral antigen yields

Published in Vaccine Weekly, July 26th, 2006

The Immune Response Corporation (IMNR) announced the development of a serum-free, chemically defined cell culture medium for the production of HIV-1 from HUT-78 cells, a human T-cell lymphoma cell line.

The development of this medium is an important step in the development of a vaccine utilizing whole-inactivated HIV to stimulate the human immune system against the virus. The Immune Response Corporation is currently evaluating this approach for a therapeutic vaccine in clinical trials of its second-generation HIV immunotherapy IR103. This technology will also be utilized toward the development of a preventive vaccine candidate.

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