Vaccine Weekly

Meningitis Vaccine - Pneumococcal vaccination in infancy reduces nasopharyngeal pneumococcal carriage

Multiple Myeloma Pathogenesis - Oncogenic RAS mutations in myeloma cells induce cox-2 expression

Rheumatologic Diseases -  Mycobacterium tuberculosis can affect musculoskeletal system

Tetanus Vaccine - Vaccine does not prevent uptake of tetanus toxin binding fragment by motor neurons

Anthrax Vaccine - Biological warfare vaccines generate long-lasting T cell responses

Anthrax Vaccine - LigoCyte awarded an additional $2.3M contract for mucosal anthrax vaccine

Anthrax Vaccine - No link was found between anthrax vaccination and risk of optic neuritis

Apoptosis - Tumor cell apoptosis protected by 9-O-acetyl GD3

Avian Influenza - Baxter initiates study with cell-based candidate H5N1 pandemic vaccine

Avian Influenza - PowderMed submits regulatory documentation to conduct a clinical trial of a bird flu vaccine

Bladder Cancer - Bladder cancer apoptosis induced by intravesical N-(4-hydroxyphenyl) retinamide and adriamycin

Breast Cancer - Rho GTPase regulator promotes breast cancer cell invasiveness

Business Update - Bangalore, India-based Strides Arcolab receives fifth HIV product approval from WHO

Business Update - Board of Techedge Inc. approves company name change to China Biopharma Inc.

Business Update - DOR BioPharma announces successful completion of cGMP production milestone for RiVax

Business Update - Medical Services International to ship VScan HIV test kits into several European countries

Cancer Drugs - Terphenyl 13g exhibited more potent apoptotic and differentiating activity than resveratrol

Cancer Vaccine - Antibody therapy shows promise for CD3-positive tumors

Cancer Vaccine - Anticancer glycolipid monoclonal antibody directly induces tumor cell apoptosis

Cancer Vaccine - Chronic immunotherapy induces loss of tumor-specific CD8+ T effectors

Cancer Vaccine - Epeius Biotechnologies initiates Tri-REX Vaccination Protocols for breast cancer

Cancer Vaccine - Timely DNA vaccine plus IL-12 prevents parotid carcinomas

Cervical Cancer - Cervical cancer vaccine is result of German and United States collaboration

Cervical Cancer - Women In Government applauds federal advisory group on papilloma virus vaccine recommendations

Chickenpox Vaccine - One dose of varicella vaccine does not prevent school outbreaks

Chickenpox Vaccine - U.S. CDC committee recommends second dose of chickenpox-containing vaccine

Collaborations - Take Care Health, SSM Health Care-St Louis team to bring healthcare services to retail arena

Collaborations - Vertex, Tibotec announce plans for initiative to increase awareness of hepatitis C

Drug Delivery - pSivida files U.K. patent application for drug delivery platform that can act as adjuvant

Fibrosarcoma - Fibrosarcoma metastasis inhibited by caffeic acid phenethyl ester

Gene Delivery - Chitosan oligosaccharide-stearic acid micelles for gene delivery are developed

Gene Therapy - CFTR gene therapy improves pulmonary hypoplasia linked to diaphragmatic hernia

Geriatrics - Emergency medical services program to promote health of older adults falls short

Glioma Vaccine - IL-13 receptor alpha 2 peptide analogues improve antiglioma CTL responses

HIV/AIDS Research - Women who transmit HIV to their offspring were less likely to have autologous neutralizing antibody

HIV/AIDS Vaccine - Lentiviral vectors expressing HIV-1 Rev/Env or HIV-1gp120 generate durable immune responses

HIV/AIDS Vaccine - Vaccine-induced immune responses reduce SIVmac239 concentrations

Healthcare Coverage - Health insurance company WellPoint to cover Merck's human papilloma virus vaccine Gardasil

Healthcare Coverage - Uninsured children are less likely to be current on vaccinations

Human Papillomavirus - High prevalence of HPV-58 and -82 and no HPV-18 found in Tunisian prostitutes

Immunology - IL-2 signals during priming are needed for expansion of CD8+ memory T cells

Immunology - Mucosal dendritic cells play key role in compartmentation of immune response to enteric antigens

Immunotherapy - DMXAA treatment of non-immunogenic tumor does not synergize with immunotherapy

Influenza Vaccine - Influenza immunization is safe for infants, toddlers, and their contacts

Influenza Vaccine - Influenza vaccine is safe but less effective in systemic lupus erythematosus patients

Influenza Vaccine - Technology could produce new human flu vaccines quicker and cheaper than current methods

Influenza Vaccine - U.S. FDA approves use of reverse genetics technology to produce influenza vaccine strains

Kidney Cancer Vaccine - Peptide-pulsed dendritic cell vaccine induces immune responses in metastatic renal cancer

Leukemia - Leukemia apoptosis induced by novel nitrogen heterocycle compound

Leukemia - Leukemia treated by MDM2 antagonists alone or in combination with chemotherapeutic drugs

Measles Vaccine - Integrated campaign launched to protect more than 3.5 million children in Angola

Measles Vaccine - Measles catch-up and follow-up campaigns in Afghanistan are cost effective

Measles Vaccine - Measles virus with hemagglutinin mutation cannot use receptor CD46 efficiently

Mucosal Immunization - Dentavax stimulates cellular and humoral systemic and mucosal immune responses

Multiple Myeloma Pathogenesis - Recurrent infections promote growth of multiple myeloma cells

Neisseria Meningitidis - Mortality is greater from Neisseria meningitidis outbreaks than from sporadic cases in U.S.

Pancreatic Cancer - Growth factor-specific monoclonal antibodies inhibit pancreatic tumor growth

Pancreatic Cancer - Pharmexa granted orphan drug designation for GV1001 in Europe

Personnel - Iomai appoints Thomas Martin Vernon, Jr., MD, and F. Weller Meyer to board of directors

Product Licensing - Inovio exercises license with RMR related to delivery of gene-based therapeutics into skin

Prostate Cancer - Cell Genesys reports positive phase I/II results for vaccine for prostate cancer

Rotavirus Epidemiology - Rotavirus is important cause of diarrhea-related hospitalization in U.S. children

Schistosomiasis Vaccine - Impact of IL-1 and IL-6 in primary schistosomiasis is examined

Smallpox Vaccine - Vaccinia virus ketch protein A55 affects outcome of infection

Smallpox Vaccine - Vaccinia virus Western Reserve protein B14 is intracellular virulence factor

Stem Cell Research - Geron presents new data on developing therapeutic products from human embryonic stem cells

Vaccine Adjuvant - Vaccine adjuvants with TLR3 or TLR9 agonists complexed to liposomes provide efficient immunization

Vaccine Epidemiology - Risk factors for partial and no immunization differ in first year of life

Vector Development - Fusion protein penetrates mouse hypoglossal nuclei from transduced ependyma

Apoptosis - Researchers from Japan, the United States and the United Kingdom detail new studies and findings in the area of apoptosis