Gene Therapy
CFTR gene therapy improves pulmonary hypoplasia linked to diaphragmatic hernia
Published in Vaccine Weekly, August 2nd, 2006
According to a study from the United States, "Congenital diaphragmatic hernia (CDH) may be an ideal candidate disease for in utero gene therapy as disrupted fetal lung growth plays a significant role in disease outcome. We previously demonstrated that transient in utero overexpression of CFTR during fetal development resulted in lung epithelial proliferation and differentiation. We hypothesized that gene therapy with CFTR would improve the pulmonary hypoplasia associated with congenital diaphragmatic hernia (CDH)."
"CDH was induced by the...
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Source: Vaccine Weekly (2006-08-02)
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