Breast Cancer Vaccine
CIITA-induced MHC class II expression leads to breast tumor rejection
Published in Vaccine Weekly, August 9th, 2006
Scientists writing in the journal Clinical Cancer Research report, "We have shown previously that the MHC class II-negative murineTS/A adenocarcinoma is rejected in vivo if induced to express MHC class II molecules by transfection of the MHC class II transactivator CIITA. In this study, we explored the immunologic basis of tumor rejection and the correlation between histopathology of tumor tissue and immune rejection."
"Stable TS/A-CIITA transfectants were generated and...
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Source: Vaccine Weekly (2006-08-09)
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