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Cancer Treatment

Findings from the United Kingdom, Switzerland and France in cancer treatment provide new insights

Published in Vaccine Weekly, August 9th, 2006

Reports from the United Kingdom, Switzerland and France highlight recent research in cancer treatment.

Study 1: Scientists have identified a major histocompatibility complex class I-restricted T-cell epitope in the tumor-associated antigen, 5T4.

According to their report, "5T4 is a surface glycoprotein expressed on placental trophoblasts and also on a wide range of human carcinomas. Its highly restricted expression on normal tissues and broad distribution on many carcinomas make 5T4 a promising target for cancer immunotherapy."

"In the current study, we set out to investigate whether a 5T4-specific cytotoxic T lymphocyte (CTL)...

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