Published in Vaccine Weekly, August 9th, 2006
Study 1: Scientists have identified a major histocompatibility complex class I-restricted T-cell epitope in the tumor-associated antigen, 5T4.
According to their report, "5T4 is a surface glycoprotein expressed on placental trophoblasts and also on a wide range of human carcinomas. Its highly restricted expression on normal tissues and broad distribution on many carcinomas make 5T4 a promising target for cancer immunotherapy."
"In the current study, we set out to investigate whether a 5T4-specific cytotoxic T lymphocyte (CTL)...
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Source: Vaccine Weekly (2006-08-09)
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