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Cytomegalovirus

Research from the United States and France add new data to cytomegalovirus body of knowledge

Published in Vaccine Weekly, August 9th, 2006

New findings from the United States and France describe advances in cytomegalovirus.

Study 1: Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication.

According to a study from the United States, "Human cytomegalovirus (HCMV) expresses several proteins that manipulate normal cellular functions, including cellular transcription, apoptosis, immune response, and cell cycle control. The IE2 gene, which is expressed from the HCMV major immediate-early (MIE) promoter, encodes the IE86 protein."

"IE86 is a multifunctional protein that is essential for viral replication,"...

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