Vaccine Weekly

Autoimmune Disease - Antibodies to polysaccharides protect against severe infection in C2 deficiency

Mononucleosis Risk Factors - Infectious mononucleosis vaccine may need only to reduce viral load

Proteomics - Mouse neural stem cells that stably express human nerve growth factor are characterized

Tuberculosis Vaccine - Complications associated with BCG vaccine in Ireland are outlined

Avian Influenza - Bird flu virus NS1 gene was progressively truncated after circulation in poultry

Avian Influenza - HepaLife continues bird flu vaccine development, discusses new report on influenza

Business & Finance - Dynavax reports net loss of $15.3 million in second quarter

Business & Finance - Hemispherx wins AMEX compliance approval, looks ahead to promising pharmaceutical lineup

Business Update - Chembio applies for CLIA Waiver for SURE CHECK HIV 1/2, go-ahead would expand domestic marketing

Business Update - Chembio features Dual Path Platform at American Association for Clinical Chemistry Expo

Business Update - Medical Services reports intent to submit TB, hepatitis test kits for European Union approval

Cancer Therapy - Lonafarnib showed anticancer activity

Cancer Vaccine - Activity of CD20 monoclonal antibodies is linked to unique CD20 epitopes

Cancer Vaccine - Modified tyrosinase-related protein epitope is not efficacious in tumor model

Cancer Vaccine - N-terminal GRP94 fragment is sufficient for peptide presentation via antigen-presenting cells

Cancer Vaccine - Secondary immunization delays advanced-stage tumor progression

DNA Vaccine - Plasmid size up to 20 kbp does not limit lung gene transfer using DNA nanoparticles

Dengue Vaccine - Dengue 2 virus nonstructural glycoprotein NS1 was expressed in Pichia pastoris

Finance - Monogram Biosciences announces Q2 2006 revenue of $13.4 million, up 8% from Q2 2005

Gastroenterology - Memory CD4+ T cell subsets persist after helminth infection to protect against challenge

Glioma Vaccine - Dendritic cells pulsed with glioma lysates increase survival of tumor-bearing mice

HIV/AIDS Long-Term Nonprogressors - Anti-CCR5 antibody induction may protect against HIV progression in long-term nonprogressors

HIV/AIDS Perinatal Transmission - Maternal autologous neutralizing antibody protective against perinatal HIV-1 transmission

HIV/AIDS Research - Viral Genetics' study of protein-based therapy for treating AIDS yields significant results

HIV/AIDS Vaccine - Cleaved, trimeric HIV-1 envelope glycoprotein vaccine antigens have been produced

HIV/AIDS Vaccine - Hematopoietic stem cells provide protection against HIV infection

HIV/AIDS Vaccine - HIV-neutralizing monoclonal antibody 4E10 recognizes N-terminal sequences on native antigen

HIV/AIDS Vaccine - Locally elicited immune responses at mucosal entry sites likely to favor immune activation

HIV/AIDS Vaccine - Relative neutralization sensitivity/resistance is HIV-1 type B isolate reproducible property

HIV/AIDS Vaccine Trials - Sensitivity analyses in HIV vaccine trial compares outcomes only existing in patient subsets

Hepatitis B Virus - China immunizes millions of children against hepatitis B in historic collaboration

Human Cytomegalovirus Vaccine - Researchers outline an innovative method for creating a human cytomegalovirus vaccine

Infectious Diseases - SARS and infectious diseases still a threat to healthcare workers, even with protective clothing

Infectious Diseases - Viral amino acid envelope mutations closely correlate with pathogenicity

Influenza - MedImmune begins shipping live intranasal flu vaccine for 2006-2007 after U.S. FDA release

Influenza Vaccine - Computer model addresses pandemic influenza in 21st century

Influenza Vaccine - Lessons learned from the 2001-2004 Maryland influenza prevention seasons are presented

Influenza Vaccine - Vaccine redistribution model was developed to prevent influenza vaccine shortage

Influenza Virus Drug Development - Cyanobacteria exopolysaccharide inhibits influenza virus-induced pneumonia

Leukemia - Calcineurin-dependent IL-2 production inhibits CD4+CD25+ regulatory T cell function

Lung Cancer Vaccine - GM-CSF-producing vaccine after docetaxel improves survival of mice with Lewis lung carcinoma

Melanoma - Melanoma tumor growth and metastasis inhibited by GPR56

Melanoma Vaccine - Allogeneic cell vaccine shows promise against melanoma in phase 1 trial

Melanoma Vaccine - CpG-ODN enhances immune effects of dendritic cell vaccine in melanoma

Obesity Vaccine - Male rats immunized with a vaccine ate normally yet gained less weight and had less body fat

Pediatric Vaccine - Financial sustainability planning for immunization in Cambodia is discussed

Pediatric Vaccine - Parental literacy and religion influence immunization status of children in India

Pneumococcal Vaccine - State vaccine financing policies affect uptake of pneumococcal conjugate vaccine

Prostate Cancer Vaccine - Provenge plus bevacizumab elicits immune response in prostate cancer

Proteomics - Improved methods to purify mammalian proteins with poor E. coli expression have been developed

Sepsis Therapy - Liposome-mediated IL-10 gene transfer increases survival in sepsis model

Sjogren-Larsson Syndrome - Gene therapy restores fatty aldehyde dehydrogenase in Sjogren-Larsson syndrome

Tuberculosis Diagnosis - Whole-blood IFN-gamma assay to detect latent TB infection has performance limitations

Tuberculosis Vaccine -  Mycobacterium tuberculosis proteins gain access to cytosolic antigen-processing pathway

Virology - Norovirus replication in human cell line was investigated

Adenovirus - New findings from the United States and United Kingdom in the area of adenovirus described

Anthrax - New data from the United States and People's Republic of China lluminates research in anthrax

Anthrax - Researchers from the United States report details of new studies and findings in the area of anthrax

Apoptosis - Researchers from the United States and Japan report recent findings in apoptosis

Cancer Treatment - Data from France, the South Korea and the People's Republic of China advance knowledge in cancer treatment research

Cancer Treatment - New findings from the United States and Germany in the area of cancer treatment described