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Melanoma

Researchers' data from Germany and the United States advance melanoma research

Published in Vaccine Weekly, August 30th, 2006

Data on melanoma are outlined in reports from Germany and the United States.

Study 1: A study from Germany has reported on the therapeutic efficacy of antigen-specific vaccination and toll-like receptor (TLR) stimulation against established transplanted and autochthonous melanoma in mice.

"Malignant melanoma is an attractive model disease for the development of antigen-specific immunotherapy because many antigens recognized by tumor-specific T cells have been identified.

"In C57BL/6 mice, genetic immunization with recombinant adenovirus encoding xenogeneic human tyrosinase-related protein 2 (Ad-hTRP2) induces protective but not...

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