Cancer Vaccine
Double-stranded RNA poly(I:C) may be potent peptide vaccine adjuvant
Published in Vaccine Weekly, August 30th, 2006
According to recent research published in the journal Cancer Immunology Immunotherapy, "Due to the inherent lack of immunogenicity of peptides, it is generally recognized that the strong inflammatory signals that are required to elicit specific responses against peptide-based therapeutic tumor vaccines may not be provided by the standard/conventional vaccine adjuvants. In this study, we have demonstrated dsRNA in the form of synthetic pI:C as a potent adjuvant to enhance the specific anti-tumor immune responses against a peptide-based vaccine."
"When...
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Source: Vaccine Weekly (2006-08-30)
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