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Measles Vaccine

Maternal antibody inhibits response to measles vaccination at birth

Published in Vaccine Weekly, September 6th, 2006

Maternal antibody inhibits both cellular and humoral immunity in response to measles vaccination at birth.

"Maternal antibody prevents the use of live, attenuated measles vaccine (LAV) before six to nine months of age, but vaccinated six-month-old infants can mount a T-cell response. An infant macaque model was used to study the immune response to LAV in the newborn in the presence or absence of maternal antibody," scientists writing in the journal Virology report.

"Four newborn monkeys without detectable maternal antibody and 9 newborns with passive measles antibody were vaccinated with LAV," explained Mary Premenko-Lanier and colleagues at...

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