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Multiple Myeloma Vaccine

Idiotype-specific immunotherapy in multiple myeloma is focus of review

Published in Vaccine Weekly, September 6th, 2006

Researchers review idiotype-specific immunotherapy in multiple myeloma in a recent issue of Haematologica.

According to the review from Norway, "Multiple myeloma (MM) remains a difficult-to-cure cancer and less than 20% of patients achieve long-term survival irrespective of the treatment delivered, including high-dose chemotherapy. Thus, new treatment modalities are urgently needed."

Bjarne Bogen and colleagues at the University of Oslo wrote, "Myeloma cells produce a monoclonal immunoglobulin (Ig), which is a truly tumor-specific antigen. The tumor-specific antigenic determinants are localized in the variable regions of the monoclonal Ig and...

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