Published in Vaccine Weekly, September 6th, 2006
According to a report from Germany, "The incidence of local reactions to diphtheria-tetanus-acellular pertussis (DTaP) vaccines in infants and toddlers increases with each subsequent dose, and entire thigh swellings (ETS) have been reported. Lowering the amount of antigen or of adjuvant may decrease the reactogenicity of DTaP while maintaining a protective immune response."
"Following priming with three doses of a DTAP vaccine during infancy, the safety, reactogenicity...
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