Published in Vaccine Weekly, September 6th, 2006
Study 1: Vaccination with peptide mimotopes induced IgG antibodies against the GD2 carbohydrate tumor antigen.
According to recent research from Austria, "The disialoganglioside GD2, a carbohydrate antigen, is expressed on all tumors of neuro-ectodermal origin, including melanoma, neuroblastoma, sarcoma, and small cell lung cancer. Due to its specific expression on tumor surfaces, GD2 is an attractive target for immunotherapies. The mouse/human chimeric anti-GD2 mAb ch14.18 is already applied in melanoma and neuroblastoma trials as a passive...
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Source: Vaccine Weekly (2006-09-06)
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