Published in Vaccine Weekly, September 20th, 2006
"Although CD4+ Type-1T helper (Th1) cells secreting interferon-gamma (IFN-gamma) appear to play an essential role in promoting durable antitumor immunity, we have previously shown that patients with cancer exhibit dysfunctional Th1-type responses against epitopes derived from tumor antigens, such as MAGE-A6.
"Here, we engineered human DCs to...
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