Influenza Vaccine
Complex T cell memory repertoires participate in recall responses at antigen load extremes
Published in Vaccine Weekly, September 20th, 2006
According to a report from the United States, "The CD8 T cell memory response to the HLA-A2-restrieted influenza epitope M158-66 can be an instructive model of immune memory to a nonevolving epitope of a frequently encountered pathogen that undergoes clearance. This memory repertoire can be complex, composed of a large number of clonotypes represented at low copy numbers, while maintaining a focus on the use of VB17 T cell receptors with identified antigen recognition motifs."
"Such a repertoire structure might provide a panoply of...
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Source: Vaccine Weekly (2006-09-20)
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