Cancer Treatment
Studies from the United States and speramba@uic describe new findings in cancer treatment research
Published in Vaccine Weekly, September 20th, 2006
Study 1: A modified tyrosinase-related protein 2 epitope generates high-affinity tumor-specific T cells but does not mediate therapeutic efficacy in an intradermal tumor model.
"The generation of tumor-specific T cells is hampered by the presentation of poorly immunogenic tumor-specific epitopes by the tumor. [In our report], we demonstrate that, although CD8+ T cells specific for the self/tumor antigen tyrosinase-related protein 2 (TRP2) are readily detected in tumor-bearing hosts, vaccination of either tumor-bearing or naive mice with an epitope derived...
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Source: Vaccine Weekly (2006-09-20)
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