Mosquito-Borne Disease
Aedes aegypti peritrophic matrix protein is identified as heme-binding protein
Published in Vaccine Weekly, September 27th, 2006
According to a study from the United States and Brazil, "The gene Aedes aegypti intestinal mucin 1 (AeIMUC1) encodes a putative peritrophic matrix (PM) protein that is expressed in the midgut of mosquito larvae and adults and is upregulated in response to exposure to heavy metals. The AeIMUC1 protein has a predicted secretory signal peptide and three putative chitin-binding domains (CBDs) with an intervening mucin-like domain."
"Immunofluorescence and immunoelectron microscopy experiments established that AeIMUC1 is a bona fide PM...
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Source: Vaccine Weekly (2006-09-27)
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