Published in Vaccine Weekly, October 4th, 2006
Study 1: Immunization with HIV-1SF162-derived envelope gp140 proteins does not protect macaques from heterologous simian-human immunodeficiency virus SHIV89.6P infection.
According to recent research from the United States, "Immunization by the SF162gp140 or the Delta V2gp140 HIV-1 envelope proteins results in the generation of strong homologous neutralizing antibodies (NAbs) that offer similar degree of protection from disease-development to macaques challenged with homologous virus. These two immunogens elicit weak cross-reactive NAbs and their effectiveness against heterologous...
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Source: Vaccine Weekly (2006-10-04)
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