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Avian Influenza

Live H5N1 bird flu virus vaccines show protection in animal studies

Published in Vaccine Weekly, October 4th, 2006

When tested in mice and ferrets, experimental vaccines based on live, weakened versions of different strains of the H5N1 avian influenza virus were well-tolerated and protected the animals from a deadly infection with naturally occurring H5N1 flu viruses. The findings are also encouraging because they demonstrate the ability to create a vaccine based on one particular strain of the H5N1 flu virus that could potentially protect against different emerging H5N1 flu strains.

Senior investigator Kanta Subbarao, MD, MPH, and co-chief Brian Murphy, MD, both of the Laboratory of Infectious Diseases at the National Institute of Allergy and Infectious Diseases (NIAID), part of...

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