Published in Vaccine Weekly, October 18th, 2006
According to scientists China, "Epithelial ovarian carcinoma is the most lethal gynecological cancer. However, little is known about the molecular mechanisms underlying the disease development and progression. In this study, we found that the expression of pigment epithelium-derived factor (PEDF) was greatly reduced in ovarian tumors and in ovarian cancer cell lines when compared with their normal precursor, ovarian surface epithelium (OSE)."
"In addition, we showed that exogenous PEDF inhibited the growth of...
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