Cancer Vaccines

Research on cancer vaccines detailed by scientists at Chinese Academy of Medical Sciences

Published in Vaccine Weekly, November 1st, 2006

Data detailed in "Induction of protective and therapeutic antitumour immunity using a novel tumour-associated antigen-specific DNA vaccine" have been presented. "DNA vaccination has become an attractive immunization strategy against cancer. However, a major problem of DNA vaccination is its limited potency to be taken up by the antigen-presenting cells," scientists in Beijing, People's Republic of China report.

"In contrast, loss of immunogenic epitopes of tumor cells has urged the development of vaccines against multiple epitopes. In this study, we developed a novel strategy for the APC to efficiently cross-present a fusion tumor antigen, which contains both MHC class...

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Source: Vaccine Weekly (2006-11-01)

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