Arthritis Vaccine
Immature dendritic cells suppress collagen-induced arthritis
Published in Vaccine Weekly, November 8th, 2006
According to scientists writing in the Journal of Immunology, "Dendritic cells (DCs) are specialized APCs with an important role in the initiation and regulation of immune responses. Immature DCs (iDCs) reportedly mediate tolerance in the absence of maturation/inflammatory stimuli, presumably by the induction of regulatory T cells."
"In this study, we show for the first time that repetitive iDC injections trigger the expansion of a novel regulatory population with high immunomodulatory properties, able to protect mice from...
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Source: Vaccine Weekly (2006-11-08)
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