Patents

Mirus Bio awarded broad European patent covering intravascular injection method

Published in Vaccine Weekly, November 29th, 2006

Mirus Bio Corporation announced the grant of European Patent EP1246649 titled "Intravascular Delivery of Nucleic Acid." The patent broadly covers Pathway IV, a method to deliver therapeutic genes to muscle and other tissues via the blood stream. This platform can be used to deliver a range of nucleic acids, including plasmid DNA (pDNA), small interfering RNA (siRNA), and viral vectors.

The Pathway IV delivery technique is elegant in its simplicity and is practical for clinical applications. With blood flow in an arm or leg temporarily occluded by a tourniquet, a pDNA-saline solution is rapidly injected intravenously. This elevates the pressure within the occlusion zone,...

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Source: Vaccine Weekly (2006-11-29)

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