DNA Vaccines
Reports from Bio-Safety Research Institute advance knowledge in DNA vaccines
Published in Vaccine Weekly, January 10th, 2007
Data detailed in "Differential segregation of protective immunity by encoded antigen in DNA vaccine against pseudorabies virus" have been presented. "A murine model immunized with plasmid DNA vaccine expressing three glycoproteins pCIgB, pCIgC and pCIgD were used to examine the relative potency of major glycoproteins as well as the contribution of immunological parameters in providing protective immunity against the pseudorabies virus (PrV). Among the three glycoprotein-encoded plasmid DNA vaccines, pCIgB produced the strongest response of PrV-specific IgG in the sera. pCIgB and pCIgD also induced a contrast pattern of immunity that was biased to the Th1 and Th2 types, respectively. pCIgC...
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Source: Vaccine Weekly (2007-01-10)
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