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Vaccinia Virus

Recent findings from Academia Sinica, Taiwan, illuminate research in vaccinia virus

Published in Vaccine Weekly, January 17th, 2007

Investigators from Academia Sinica, Taiwan, have published new vaccinia virus data.

Study 1: The envelope G3L protein is essential for entry of vaccinia virus into host cells.

According to recent research published in the Journal of Virology, "The vaccinia virus G3L/WR079 gene encodes a conserved protein with a predicted transmembrane domain. Our proteomic analyses of vaccinia virus revealed that G3L protein is incorporated into intracellular mature virus; however, the function of G3L protein in the vaccinia virus life cycle has not been investigated."

"In this study, a recombinant vaccinia virus, AWL, expressing G3L...

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