Cancer Vaccines
Reports from Osaka University describe recent advances in cancer vaccines
Published in Vaccine Weekly, January 24th, 2007
New investigation results, "Intrahepatic delivery of alpha-galactosylceramide-pulsed dendritic cells suppresses liver tumor," are detailed in a study published in Hepatology. "Alpha-galactosylceramide, a glycosphingolipid, mediates interaction of dendritic cells (DCs) and NKT cells, leading to activation of both innate and acquired immunity. For cancer treatment, conventional DC-based vaccine has been tried, but its clinical efficacy is limited against liver cancer," scientists in Suita, Japan report.
"Intrahepatic injection of alpha-Galactosylceramide-pulsed DCs (alphaGCDC) has not yet been tested in the liver that contains abundant immune cells such as NK, NKT, and T...
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Source: Vaccine Weekly (2007-01-24)
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