Rotavirus Vaccines
Research on rotavirus vaccines described by scientists at Cincinnati Children's Hospital, Division of Infectious Diseases
Published in Vaccine Weekly, January 31st, 2007
Scientists discuss in "Reductions in cross-neutralizing antibody responses in infants after attenuation of the human rotavirus vaccine candidate 89-12" new findings in rotavirus. "The G1P1A[8] rotavirus vaccine candidate 89-12, the precursor to Rotarix, stimulated high titers of neutralizing antibodies to non-G1/P1A[8] serotypes of human rotavirus in naturally infected subjects before attenuation by cell-culture passages. These responses were greatly diminished in young infants (median age, 11 weeks) administered the attenuated vaccine," scientists in the United States report.
"Because of the possibility of improved responses in older infants, the immunogenicity of the...
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Source: Vaccine Weekly (2007-01-31)
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