Cancer Vaccines

New findings in cancer vaccines described from Korea University

Published in Vaccine Weekly, February 7th, 2007

Current study results from the report, "Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination," have been published. "Immunotherapy and chemotherapy are generally effective against small tumors in animal models of cancer. However, these treatment regimens are generally ineffective against large, bulky tumors," scientists in South Korea report.

"We have found that a multimodality treatment regimen using DNA vaccination in combination with chemotherapeutic agent epigallocatechin-3-gallate (EGCG), a compound found in green tea, is effective in inhibiting large tumor growth. EGCG was found to induce tumor cellular apoptosis...

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Source: Vaccine Weekly (2007-02-07)

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