Amyotrophic Lateral Sclerosis Vaccines
Reports outline amyotrophic lateral sclerosis vaccines study findings from Laval University
Published in Vaccine Weekly, April 4th, 2007
A report, "Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis," is newly published data in Proceedings of the National Academy of Sciences of the United States of America. "There is emerging evidence for the existence of secretory pathways for superoxide dismutase (SOD1) mutants linked to amyotrophic lateral sclerosis (ALS) and for neurotoxicity of extracellular mutant SOD1. This evidence led us to test immunization protocols aiming to reduce the burden of extracellular SOD1 mutants in nervous tissue of mice models of ALS, by using bacterially purified recombinant SOD1 mutant protein as an immunogen," scientists in...
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Source: Vaccine Weekly (2007-04-04)
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