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Pneumococcal Disease Vaccines

Studies from Wyeth update current data on pneumococcal disease vaccines

Published in Vaccine Weekly, May 9th, 2007

Fresh data on pneumococcal disease are presented in the report "Brief review of the clinical effectiveness of PREVENAR against otitis media. Pre-licensure trials in Finnish and US infants demonstrated that PREVENAR was associated, respectively, with a 6% (95% CI, -4% to 16%) and an 8.9% (95% CI, 5.8-11.8%) overall reduction in clinical AOM incidence. Long-term follow-up of these cohorts revealed that there was an approximately 10-50% vaccine efficacy against recurrent otitis media or for the prevention of tympanostomy tube placement," researchers in France report.

"In surveillance reports from the USA that followed infants with serious AOM, generalized PREVENAR...

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